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Measuring AI’s capability to accelerate biological research
OpenAI introduces a real-world evaluation framework to measure how AI can accelerate biological research in the wet lab. Using GPT-5 to optimize a molecular cloning protocol, the work explores both the promise and risks of AI-assisted experimentation.
Strengthening cyber resilience as AI capabilities advance
OpenAI is investing in stronger safeguards and defensive capabilities as AI models become more powerful in cybersecurity. We explain how we assess risk, limit misuse, and work with the security community to strengthen cyber resilience.
The state of enterprise AI
Key findings from OpenAI’s enterprise data show accelerating AI adoption, deeper integration, and measurable productivity gains across industries in 2025.
How confessions can keep language models honest
OpenAI researchers are testing “confessions,” a method that trains models to admit when they make mistakes or act undesirably, helping improve AI honesty, transparency, and trust in model outputs.
Mixpanel security incident: what OpenAI users need to know
OpenAI shares details about a Mixpanel security incident involving limited API analytics data. No API content, credentials, or payment details were exposed. Learn what happened and how we’re protecting users.
GPT-5 and the future of mathematical discovery
UCLA Professor Ernest Ryu and GPT-5 solved a key question in optimization theory, showcasing AI’s role in accelerating mathematical discovery.
Early experiments in accelerating science with GPT-5
OpenAI introduces the first research cases showing how GPT-5 accelerates scientific progress across math, physics, biology, and computer science. Explore how AI and researchers collaborate to generate proofs, uncover new insights, and reshape the pace of discovery.
Strengthening our safety ecosystem with external testing
OpenAI works with independent experts to evaluate frontier AI systems. Third-party testing strengthens safety, validates safeguards, and increases transparency in how we assess model capabilities and risks.
Understanding neural networks through sparse circuits
OpenAI is exploring mechanistic interpretability to understand how neural networks reason. Our new sparse model approach could make AI systems more transparent and support safer, more reliable behavior.
Understanding prompt injections: a frontier security challenge
Prompt injections are a frontier security challenge for AI systems. Learn how these attacks work and how OpenAI is advancing research, training models, and building safeguards for users.
Introducing IndQA
OpenAI introduces IndQA, a new benchmark for evaluating AI systems in Indian languages. Built with domain experts, IndQA tests cultural understanding and reasoning across 12 languages and 10 knowledge areas.
gpt-oss-safeguard technical report
gpt-oss-safeguard-120b and gpt-oss-safeguard-20b are two open-weight reasoning models post-trained from the gpt-oss models and trained to reason from a provided policy in order to label content under that policy. In this report, we describe gpt-oss-safeguard’s capabilities and provide our baseline safety evaluations on the gpt-oss-safeguard models, using the underlying gpt-oss models as a baseline. For more information about the development and architecture of the underlying gpt-oss models, see the original gpt-oss model model card.
Advancing organizational transformation for business innovation
DNP rolled out ChatGPT Enterprise across ten core departments, achieving 95% faster patent research, 10x processing volume, 87% automation, and 70% knowledge reuse in three months.
AI in South Korea—OpenAI’s Economic Blueprint
OpenAI's Korea Economic Blueprint outlines how South Korea can scale trusted AI through sovereign capabilities and strategic partnerships to drive growth.
Expert Council on Well-Being and AI
OpenAI’s new Expert Council on Well-Being and AI brings together leading psychologists, clinicians, and researchers to guide how ChatGPT supports emotional health, especially for teens. Learn how their insights are shaping safer, more caring AI experiences.
Argentina’s AI opportunity
OpenAI and Sur Energy are exploring Argentina’s first Stargate project—an AI and clean energy collaboration that could make Argentina a Latin American leader in artificial intelligence, sustainable infrastructure, and digital innovation.
Defining and evaluating political bias in LLMs
Learn how OpenAI evaluates political bias in ChatGPT through new real-world testing methods that improve objectivity and reduce bias.
Disrupting malicious uses of AI: October 2025
Discover how OpenAI is detecting and disrupting malicious uses of AI in our October 2025 report. Learn how we’re countering misuse, enforcing policies, and protecting users from real-world harms.
Accelerating AI adoption in Europe
OpenAI and Allied for Startups release the Hacktivate AI report with 20 actionable policy ideas to accelerate AI adoption in Europe, boost competitiveness, and empower innovators.
Turning contracts into searchable data at OpenAI
OpenAI built a system to extract contract data quickly, cutting turnaround times and making it easier for teams to access the details they need.